Down Syndrome Research Foundation
Do you believe in magic? Want to know more about DSRF? We would be happy to give you a tour of our unique facility. Please contact Dawn to set up an individualized or group tour....more
DSRF - Making Dreams Happen
The Down Syndrome Research Foundation is proud to present our brand new promotional video aimed at raising awareness for our organization as well as providing information on our various programs for individuals with developmental disabilities of all ages....more
2012 Annual Report
2012 saw DSRF grow in our capacity and effectiveness in serving the Down syndrome community. Read about the highlights of our year through our interactive 2012 Annual Report....more
Why Sign with your Child?
Dr. Alberto Costa
Josephine Mills Research Awards - Exceptional Contribution to Research in Down Syndrome Award Recipient:
Alberto Costa, M.D., Ph.D.
Dr. Costa is an M.D. Ph.D trained as a neuroscientist. He is currently an Associate Professor of Medicine and Neuroscience at the University of Colorado Denver Medical School. Dr. Costa had dedicated his career to research in Down syndrome. One of his most significant accomplishments is his recent discovery that NMDA receptor antagonists are uniquely effective in ameliorating learning deficits in the Ts65Dn mouse. These results are of major significance as they suggest that NMDA receptor dysfunction plays a critical role in learning and memory deficits associated with Down syndrome and for the first time, offer the promise that NMDA receptor antagonists, such as memantine, may improve cognitive performance in individuals with DS. Dr. Costa is now leading a group of physicians and psychologists to conduct a pilot clinical trial to study the tolerability and efficacy of memantine in improving cognitive function in young adults with DS.
Dr. Costa is one of a few investigators who have moved from studies on mice to clinical trials in humans to help alleviate intellectual disabilities in DS. He has a 13 year old daughter with DS and is very involved with local and national DS organizations in the US.